The 2025 Ducati Panigale V4 S continues to use the same 1,103cc Desmosedici Stradale V4 engine, but this unit is now compliant with the Euro 5+ norms and produces 216hp at 13,500rpm. This peak power figure is up by 0.5hp and is made 500rpm higher than before. Peak torque of 120.9Nm at 11,250rpm is 2.7Nm lower than earlier and is made 1,750rpm higher in the rev range. The engine maintains the same state of tune in both the standard and ‘S’ variants.

In terms of chassis, the front frame remains identical to the outgoing model, but the rear end is all new. After a long hiatus, Ducati has incorporated a conventional swingarm. This 2025 Ducati Panigale is the first Ducati flagship supersport since the iconic 916 to not use a single-sided swingarm. Although it might not seem like it, the entire swingarm-rear wheel assembly on this Panigale V4 is claimed to be 2.7kg lighter than the previous model. 

The more capable ‘S’ variant shown here differentiates itself by providing even better equipment, such as lighter aluminium wheels, electronic suspension, as mentioned earlier, and a lithium-ion battery. All these changes result in healthy weight savings of 4kg. The ‘S’ variant tips the scale at 187kg, whereas the standard weighs 191kg. 

Earlier, the Panigale V4 S was launched at a price of Rs 36 lakh but after the GST 2.0 implementation, its price has jumped to Rs 39 lakh.